Wednesday, May 10, 2017

In Huntington's disease, traffic jams in the cell's control center kill brain cells

05/10/2017 12:47 PM EDT

nuclear transport protein RanGAP1 (red) clumps up with mutant Huntingtin protein (green) in neurons

Working with mouse, fly and human cells and tissue, Johns Hopkins University researchers report new evidence that disruptions in the movement of cellular materials in and out of a cell's control center--the nucleus--appear to be a direct cause of brain cell death in Huntington's disease, an inherited adult neurodegenerative disorder.


Full story at http://www.hopkinsmedicine.org/news/media/releases/in_huntingtons_disease_traffic_jams_in_the_cells_control_center_kill_brain_cells

Source
Johns Hopkins Medicine


This is an NSF News From the Field item.


This email was sent using GovDelivery, on behalf of: National Science Foundation Update · 4201 Wilson Boulevard · Arlington, VA 22230 · 703-292-5111 Powered by GovDelivery

No comments:

Post a Comment