Tuesday, February 28, 2017

[JAXA:0509] Announcement on the initiation of the experiment consuming probiotics(Lactobacillus casei strain Shirota) on the ISS

March 1, 2017 (JST)

Announcement on the initiation of the experiment consuming probiotics (Lactobacillus casei strain Shirota) on the International Space Station - Research on the impact on the immune system and intestinal microbiota of astronauts -

Yakult Honsha Co., Ltd. (Yakult) and the Japan Aerospace Exploration Agency (JAXA) have been jointly researching the effect of probiotics on the human immune system and intestinal microbiota in a microgravity environment*1 since FY2014. This joint research aims to contribute to maintaining and improving the health and performance of astronauts. It is also intended to make contributions toward promoting human health in general by utilizing the knowledge gained in this joint research for the development of probiotics*2 research on the ground.

It is ready to begin the world's first experiment of consecutive consumption of probiotics by crewmembers on ISS, based on the outcomes of ground-based research activities conducted from FY2014 to FY2015, and the storage test of the capsule containing freeze-dried live probiotic bacteria (Lactobacillus casei strain Shirota*3 ) on board of the ISS conducted in FY2016. It was confirmed that the number of live probiotics in the flight sample was equivalent to those in the ground control samples.

Yakult and JAXA will initiate the space experiment from 2017, which is a scientific study of the effect caused by the consecutive consumption of probiotics on the human immune system and intestinal microbiota of astronauts staying on the ISS for long periods of time.

*1 JAXA Press Releases March 19, 2014 (JST)
http://global.jaxa.jp/press/2014/03/20140319_yakult_e.html

*2 Live microorganisms which when administered in adequate amounts confer a health benefit on the host (FAO/WHO, 2001)

*3 Lactobacillus casei strain Shirota is a probiotic strain with accumulated evidences on reaching intestine alive, maintaining and improving intestinal microbiota and immune function. The US Food and Drug Administration (FDA) has accredited the strain as being Generally Recognized As Safe (GRAS).


[Reference]
62nd Japan Aerospace Environment Medical Society, 30th Japan Space Biological Science Society at Aichi Medical University on October 14, 2016.
http://global.jaxa.jp/press/2017/03/20170301_yakult.html#ref

URL:
http://global.jaxa.jp/press/2017/03/20170301_yakult.html


Yakult Honsha Co., Ltd.
National Research and Development Agency Japan Aerospace Exploration Agency (JAXA)

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