Tuesday, May 1, 2018

CRISPR/Cas9 silences gene associated with high cholesterol

05/01/2018 04:55 PM EDT

histological sections of liver from control mice

Biomedical engineers at Duke University have used a CRISPR/Cas9 genetic engineering technique to turn off a gene that regulates cholesterol levels in adult mice, leading to reduced blood cholesterol levels and gene repression lasting for six months after a single treatment. This marks the first time researchers have delivered CRISPR/Cas9 repressors for targeted therapeutic gene silencing in adult animal models.


Full story at https://pratt.duke.edu/about/news/crisprcas9-silences-gene-associated-high-cholesterol-levels-through-epigenetic-regulation

Source
Duke University


This is an NSF News From the Field item.


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